AGT gene mutations

The AGT gene is also called “angiotensinogen”, this gene is responsible for keeping essential electrolytes in balance. AGT genes can cause imbalances in these electrolytes that can lead to serious health problems, even conditions such as:

Essential hypertension
Hypertension
Preeclampsia
Acute coronary artery syndrome
Coronary artery disease
Stroke
Heart attack
Type 2 diabetes
Left ventricular hypertrophy
Myocardial infarction
Peptic ulcer hemorrhage

AGT genes are regulators of:

Blood pressure
Body fluid
Electrolyte homeostasis

Symptoms of essential electrolytes imbalances

Sodium:

Dizziness
Heat exhaustion
Low blood pressure
Rapid pulse
Mental apathy
Loss of appetite
Muscle cramps
Nausea
Vomiting
Reduced body weight
Headaches

Potassium:

Rapid irregular heartbeat
Muscle weakness
Pins and needles
Irritability
Nausea
Vomiting
Diarrhea
Swollen abdomen
Cellulite
Low blood pressure resulting from an imbalance of potassium: sodium ratio
Confusion
Mental apathy

Magnesium:

Muscle tremors or spasms
Muscle weakness
Insomnia or nervousness
High blood pressure
Irregular heartbeat
Constipation
Fits or convulsions
Hyperactivity
Depression
Confusion
Lack of appetite
Calcium deposits in soft tissue e.g. kidney stones
Low levels of magnesium are also associated with increased rates of heart attack, anxiety, and nervousness

As you can see AGT gene mutations can cause many symptoms and also lead to many diseases. Here is what they may look link, homozygous (double bad copies in red), heterozygous (1 half a bad copy in yellow):